Presentation

September 23-24, 2019 - Salles des Actes, Grand Château, Parc Valrose, Université Côte d'Azur

Announcement

The aim of the "Côte d'Azur International Workshop on Cell Mechanics: Advanced Tools and Applications to Biomedical Problems" is to bring together researchers from the fields of biology, physics, mathematics and instrumentation/engineering interested in the characterization of the mechanical properties of single living cells and of understanding the relationship between cell mechanics and biological functions. The Workshop is organized in two half-days (September 23rd & 24th) and will take place at the Salle des Actes of the Grand Château at UCA. Invited keynote speakers, selected for their internationally recognized expertise, will lead each of the four sessions where additional contributions from other invited speakers will be presented. Contributed posters will be readable throughout the Workshop and will be open for discussion during long coffee breaks. Young scientists are specifically invited to submit their work for the poster session.

Workshop description

Cell mechanics is a field which marries physical concepts and mathematical modeling to the biological nature of cell life. In the past years, increasing attention has been paid to the influence of mechanical constraints on the development and survival of cells, beyond its obvious biochemical characteristics. The findings are very exciting, showing that mechanical constraints play a complementary role to biochemical processes and have an influence which is at least as important in the life of the "chemical reactor". The Workshop will highlight the current state of knowledge on some of the aspects related to cell mechanics, on the measurement techniques and on the development of suitable instrumentation, in addition to modeling aspects. World experts will lead the different topics which will be discussed in a setting which is chosen to be sufficiently small to favour open exchanges.

Keynote speakers

  1. Jochen Guck, Max-Planck Institute for the Science of Light and the Max-Planck Center for Physics and Medicine in Erlangen, Germany - https://gucklab.com/

  2. Gijs Wuite, Molecular Biophysics Group, Faculty of Sciences/Division of Physics and Astronomy, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands - http://www.gijswuite.com/

  3. Daniel Navajas, Cellular and respiratory biomechanics, Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain - https://www.ibecbarcelona.eu/cellmech

  4. Jacky Goetz, Tumor Biomechanics, INSERM, Institut d’hématologie et d’Immunologie, Strasbourg, France - http://www.goetzlab.com/

Invited Speakers

  1. Jonathan Fouchard, Charras Lab, London Centre for Nanotechnology, University College London, London, UK - https://charraslab.com/jonathan-fouchard/

  2. Christophe Girard, Microenvironment Signalling and Cancer, INSERM, Centre Méditerranéen de Médecine Moléculaire (C3M), Nice, France

  3. Julien Husson, Hydrodynamics Laboratory (LadHyX), Department of Mechanics, Ecole polytechnique, Palaiseau, France - https://cellmechanics.jimdo.com/

  4. Benjamin Mauroy, Laboratoire J.A. Dieudonné, Université de Nice Sophia-Antipolis / CNRS, Nice, France - http://benjamin.mauroy.free.fr/wordpress/

  5. Matteo Rauzi, Institut de Biologie Valrose, Université Cote d’Azur, Nice, France - http://ibv.unice.fr/research-team/rauzi/

  6. Paul Van Liedekerke, INRIA and Sorbonne Universités, Paris VI, France - http://www.vanliedekerke.net/

23/09/2019


14:00-14.15

Speaker : Jean-Marc Gambaudo, UCA President
Title : Welcome and forewords

14:15-15.00

Speaker : Jochen Guck, MPG Erlangen, Germany
Title : Feeling for function - cell mechanical phenotyping at 1,000 cells/sec

15:00-15:30

Speaker : Jonathan Fouchard, UCL, London, UK
Title : Fast mechanical response of epithelia to compression

15:30-16:00

Speaker : Rob Arkowitz, Institut de Biologie de Valrose, UCA
Title : The Biophysics of Invasive fungal growth

16:00-17:00

Coffee & Poster

17:00-17:45

Speaker : Gijs Wuite, VU, Amsterdam, NL
Title : Acoustic Force Spectroscopy: Using sound to investigate molecules and cells

17:45-18:15

Speaker : Paul Van liedekerke, INRIA, Paris, F
Title : Mathematical modeling for understanding cell mechanics: Overview of models and recent advancements.

18:15-18:45

Speaker : Bart Smeets, Molecular Biophysics Group, Division of Mechatronics, Biostatistics and Sensors (MeBioS), KU Leuven, Leuven, Belgium
Title : The role of active tension in cell adhesion: From single cell mechanics to tissue organization

18:45-19:15

Speaker : Julien Husso, Ecole Polytechnique, Paris, F
Title : Micropipette techniques to quantify adhesive and viscoelastic properties of cells

 

24/09/2019

 

9:00-9:45

Speaker : Jacky Goetz, INSERM, Strasbourg, F
Title : Forces shape tumor metastasis

9:45-10:15

Speaker : Christophe Girard INSERM, Nice, F
Title : Role of mechanotransduction in melanoma aggressiveness and therapeutic resistance

10:15-11:15

Coffee & Posters

11:15-12:00

Speaker : Daniel Navajas IBEC, Barcelona, ES
Title : Mechanical properties of the cell niche

12:00-12:30

Speaker : Benjamin Mauroy UCA, Nice, F
Title : Emergence of the geometry of the bronchial tree: from cell behaviour during development to an optimal organ geometry

12:30-13:00

Speaker : Matteo Rauzi UCA, Nice, F
Title : Cell shape changes and mechanics driving morphogenesis during embryo development

Registration

Organizers

Gian Luca Lippi (Université Côte d'Azur) & Massimo Vassalli (Consiglio Nazionale delle Ricerche, IBF)
Co-organized by Université Côte d'Azur and Consiglio Nazionale delle Ricerche (Italy)

Address

Salles des Actes, Grand Château, Parc Valrose
28 Avenue Valrose, 06100 Nice