Lionel Gil - Institut de physique de nice, umr 7010 cnrs-uca - Keywords: Neuronal system

Lionel Gil - Institut de physique de nice, umr 7010 cnrs-uca - Keywords: Neuronal system

Contribution title: A biophysical model mimicthe spontaneous occurence of waves in developing retina

D. Karvouniari, B. Cessac and L. Gil

During embryonic development, waves of activity spontaneously propagate across the retina. These waves, ubiquitous among vertebrate species and preserved throughout the entire evolution process, are expected to play a key role in the proper wiring between the retina and the vision area in the cortex. These waves are characterized by localized groups of neurons which spontaneously become synchronized, are initiated at random points, propagate at speeds about 100 microns per second and vanish at borders which slightly vary from one occurrence to the other.

Here, we propose a mathematical model, grounded on biophysics, which enables us to numerically reproduce the wave activity and their statistical properties.