Digital summer school - From Bones to Oceans and Space

The untold stories of Biomineralization

7 - 9 July 2021

Registration is closed for this summer school

Partners
Partners
Organizing Committee: 
  • Claudine Blin, LP2M UMR7370, CNRS-UCA, Nice, France
  • Sylvie Tambutté, Centre Scientifique de Monaco, Monaco
  • Georges Lefthériotis, LP2M UMR7370, CNRS-UCA, Nice, France
Support:
COST Action EuroSoftCalcNet

Description:
Biomineralization is a highly complex and active biological process that takes into account different aspects, including molecular, cellular and integrative biology, evolution, clinical and therapeutic aspects up to societal and environmental facts. Biomineralization is also a multidisciplinary field comprising biology, chemistry, physics, medicine and environmental sciences. This Digital Summer School is intended to unveil this interdisciplinarity and will give a unique opportunity to young research fellows who wish to enter this field of research to interact with internationally renowned experts.
This Summer School is open to young scientists (PhD, post-docs and early scientists). The program is built on 3 days of courses, interactive workshops, round tables and networking. There will be time for students to present their research projects and receive feedback from the experts.
The aim of this Summer School is to promote general knowledge on all aspects of biomineralization. The course starts with fundamentals aspects of biomineralization, followed by a varied program that integrates clinical, societal and environmental aspects.

Learning Objectives:
This Digital Summer School aims to provide advanced training for PhD students and young researchers from academia and private companies. It will also foster knowledge exchange between attendees and contribute to the establishment of scientific collaborations. Specifically, this Summer School will transfer conceptual and practical know-how on the following topics: 
  • Evolutionary aspects of biomineralization
  • Basic biological and non-biological mineralization processes
  • Clinical and pathophysiological aspects of biomineralization
  • Hands-on: Techniques to assess biomineralization processes
  • Translational research in biomineralization: from gene to therapeutics
  • Societal and environmental aspects of biomineralization
Organization:
This Summer School will be 100% online and will combine pre-recorded presentations, live discussions and interactive sessions and workshops. 

Abstracts:
Students and postdocs are invited to submit an abstract to present their project and results using the link to the abstract submission form below (150 words maximum; 5 key words; no illustration; pdf file). This from has to be send to Veronique.ESCUDE@univ-cotedazur.fr. Thirty abstracts will be selected for oral presentation. Only abstracts related to mineralized tissues will be considered for this selection. Results of the selection will be communicated to the authors on June 25.

Contact and registration:
This summer school is free but registration is mandatory.
To register, you can either send an e-mail with your name; status and affiliation to Veronique.ESCUDE@univ-cotedazur.fr or use the online form below.

Registration is closed.

 

PROGRAM (CEST time)

Wednesday July 7 

9h45-10.00: Welcome and introduction of the virtual course 

10.00-12.00: Fundamental aspects of Biomineralization 
Part 1
10.00-10.05: Presentation of speakers by the chairs
10.05-10.25: Biomineralization and Evolution: Biomineral diversity and functions. Frederic Marin, France
10.25-10.45: Fundamentals of calcium-carbonate mineralization: the coral example. Sylvie Tambutté, Monaco 
10.45-11.00:  Discussion

Part 2
11.00-11.05: Presentation of speakers by the chairs
11.05-11.25:  Fundamentals of calcium-phosphate mineralization. David Magne, France
11.25-11.45:  Fundamentals of demineralization: bone resorption. Teun de Vries, Netherlands
11.45-12.00: Discussion

12.00-14.00: Break

14.00-15.00: Workshop 1 
In vivo cell imaging by confocal microscopy with pH measurements 
Contributors: Alexander Venn, Philippe Ganot, Sylvie Tambutté

15.00-15.45: Round Table Discussion 1 
Original models in mineralization (coral, egg, sponge, fish, mollusk)
Contributors: Alexander Venn, Joël Gautron, Leonor Cancela, Frédéric Marin

15.45-16.00: Break

16.00-17.15: Student’s presentations

17.15-17-45: Informal discussion, meet the mentor

Thursday July 8


10.00-12.00: Clinical aspects of Biomineralization
Part 1

10.00-10.05: Presentation of speakers by the chairs
10.05-10.25: X-linked hypophosphatemia: from pathophysiological mechanisms to therapeutic strategies. Claire Bardet, France
10.25-10.45: Lessons from rare bone diseases to understand the pathophysiology of common bone diseases. Cristina Sobacchi, Italy 
10.45-11.00:  Discussion

Part 2
11.00-11.05 : Presentation of speakers
11.05-11.25:  Metabolic diseases and cardiovascular calcifications. Said Kamel, France
11.25-11.45: Ectopic calcifications and their impact on the cardiovascular function. Magnus Bäck, Sweden
11.45-12.00: Discussion

12.00-14.00: Break

14.00-15.00:  Workshop 2
Cytometry for bone cells: application for the characterization of osteoclasts and mesenchymal cells
Contributors: Julie Cazareth, Matthieu Rouleau, Didier Zoccola, Claudine Blin

15.00-15.45: Round Table Discussion 2 
Is there a link between bone and ectopic calcifying diseases? From gene to therapeutic issues
Contributors: Georges Leftheriotis, Magnus Back, Said Kamel

15.45-16.00: Break

16.00- 17.00: Workshop 3
How to quantify biomineralization by imaging techniques in preclinical and clinical models
Contributors: Georges Leftheriotis, Didier Pisani

17.00-17-45: Informal discussion, meet the mentor

Friday July 9


10.00-12.00: Societal/environmental aspects
Part 1
10.00-10.05 : Presentation of speakers
10.05-10.25: Societal impact of biomineralization in eggshells. Joel Gautron, France
10.25-10.45: Fish as a model to study biomineralization. Leonor Cancela, Portugal
10.45-11.00:  Discussion

Part 2
11.00-11.05: Presentation of speakers
11.05-11.25: Ocean acidification and its impact on biomineralizing organisms. Alexander Venn, Monaco
11.25-11.45: Impact of space travels on bones. Laurence Vico, France
11.45-12.00: Discussion    

12.00-14.00: Break

14.00-15.00: Debriefing by the students
Interactive discussion and feedback from the attendees on the workshops

15.00-15.45: Round Table Discussion
From ideas to drugs - A startup’s story. Piero Mendez, USA

15.45-16.00: Break

16.00-17.15: Student's presentations

17.15-17-45: Informal discussion, meet the mentor

17.45-18.00: Close of the course

Registration

Registration is closed