- Address :
- Campus Sciences, Parc Valrose, Bâtiment de Biochimie,
28 Avenue Valrose
06108 Nice Cedex 2 - Phone :
- +33 492076400
- On the Internet :
- http://ibv.unice.fr
- Additional contact details :
-
General information
Affiliated institutions :Université Côte d'Azur
Centre National de la Recherche Scientifique (CNRS)
Institut national de la santé et de la recherche médicale (Inserm)
Reference : CNRS UMR 7277INSERM U1091
Departments : DS 5 : Biologie Médecine et Santé
Organization
Director(s) :- Gilles L'Allemain (Directeur adjoint)
- Stephane Noselli (Directeur)
Staff
The iBV teams address fundamental physiopathological questions including cell communication by signaling pathways, cell and tissue growth, metabolism, cell death, cell-matrix interactions, cell differentiation, stem cells, morphogenesis, cell polarity, intra- and intercellular trafficking, neurogenesis, physiology of ion channels, reproduction, cancer, diabetes, obesity, evolution of organisms, etc.
For their research, the teams use a wide variety of model organisms (Drosophila, yeast, nematodes, sea urchins, zebrafish, mice, cell lines).
For their research, the teams use a wide variety of model organisms (Drosophila, yeast, nematodes, sea urchins, zebrafish, mice, cell lines).
Publications
Collectively, iBV researchers have received more than 140 awards and distinctions from national and international organizations:
3 European Research Council (ERC) grants, 13 teams with the ATIP - AVENIR label, 2 LanEx (including SIGNALIFE for which the iBV is the leader), 3 members of the European Molecular Biology Organization (EMBO), 4 EMBO Young Investigators, 2 HFSP Career Award Development Awards, 1 JDRF Career Development Award, 1 CNRS silver medal and 5 CNRS bronze medals, 2 Inserm Prize laureates, 8 Prizes from the French Academy of Sciences, 1 Prize from the French Academy of Medicine, 1 Prize from the Bettencourt Schueller Foundation, 2 Prizes from the Schlumberger Foundation, 1 Chair of Excellence.
3 European Research Council (ERC) grants, 13 teams with the ATIP - AVENIR label, 2 LanEx (including SIGNALIFE for which the iBV is the leader), 3 members of the European Molecular Biology Organization (EMBO), 4 EMBO Young Investigators, 2 HFSP Career Award Development Awards, 1 JDRF Career Development Award, 1 CNRS silver medal and 5 CNRS bronze medals, 2 Inserm Prize laureates, 8 Prizes from the French Academy of Sciences, 1 Prize from the French Academy of Medicine, 1 Prize from the Bettencourt Schueller Foundation, 2 Prizes from the Schlumberger Foundation, 1 Chair of Excellence.
Equipments
The iBV hosts several cutting-edge technological platforms including imaging (PRISM, IBiSA), flow and cytometry and cell sorting, molecular biology and protein purification, histopathology, automatic preparation of various biological media, L2 & L3 containment rooms, functional testing centers and bioinformatics.
These platforms are equipped with the most recent technologies, some of which have been developed in-house by iBV engineers.
These platforms are equipped with the most recent technologies, some of which have been developed in-house by iBV engineers.
Partnerships
International relations
The iBV manages more than 70 research contracts or collaborations with the EU (ERC, Marie Curie ...), ATIP-Avenir, ANR, HFSP, JDRF, ARC, InCA, LNCC, FRM, AFM, ANRS, FRC , FdF, Cancéropole PACA, CR PACA, CG06) but also with Harvard Medical School, MIT, NIH, NSF, Berkeley, UCLA, Max-Planck Institute, EMBO, Welcome Trust Center, Karolinska Institute and manufacturers (Astra Zeneca , Lilly, Novonordisk, etc.), thus ensuring a continuum between basic and clinical research.
Member of the GDR2588 Functional Microscopy of the Living research group, and the Opti'Tec (2008) and Eurobiomed (2011) clusters.
Patents: 17 (since 2005) + 1 start-up
Initiator of LabEx SIGNALIFE, 2012 Laureate (Coordinator: Stéphane Noselli)
Member of the GDR2588 Functional Microscopy of the Living research group, and the Opti'Tec (2008) and Eurobiomed (2011) clusters.
Patents: 17 (since 2005) + 1 start-up
Initiator of LabEx SIGNALIFE, 2012 Laureate (Coordinator: Stéphane Noselli)
Industrial relations
During the period 2011-2016, iBV teams filed 27 patents (6 worldwide, 2 European, 3 American, 1 Japanese and 15 French), of which 10 are pending certification (3 worldwide, 1 American, 1 Japanese and 3 French).
As part of the recognition of their research, the iBV teams have also secured research grants from the private sector (TherAchon, AXA, Galderma, GSK, Merck, Novonordisk, Roche, Servier, Yves Saint-Laurent).
Finally, Ms. Elvire Gouze, team leader at iBV, is cofounder of a biotech (TherAchon), currently hosted at iBV, which has raised over $35M in funds earmarked for future clinical studies in the fight against achondroplasia (dwarfism).
As part of the recognition of their research, the iBV teams have also secured research grants from the private sector (TherAchon, AXA, Galderma, GSK, Merck, Novonordisk, Roche, Servier, Yves Saint-Laurent).
Finally, Ms. Elvire Gouze, team leader at iBV, is cofounder of a biotech (TherAchon), currently hosted at iBV, which has raised over $35M in funds earmarked for future clinical studies in the fight against achondroplasia (dwarfism).
Key figures
The Valrose Institute of Biology was born in 2012 from the merger of the CNRS UMR6543 unit (120 staff) and the Inserm unit (40). Now, the iBV has nearly 300 staff (50% permanent) hosted on 2 campuses (Valrose and Pasteur) and 3 buildings. The iBV is home to more than 110 researchers (>90 permanent and 20 postdocs), nearly 60 technicians and administrative staff, around 50 thesis students and around 20 masters, divided into 28 research teams and 6 technical platforms.
Additional information
Health
Developmental Biology of organs
Biogenetics (reproduction, neuroscience, kidney)
Molecular pathology (obesity, diabetes, cancer)
Bioengineering (dwarfism, bone)
Developmental Biology of organs
Biogenetics (reproduction, neuroscience, kidney)
Molecular pathology (obesity, diabetes, cancer)
Bioengineering (dwarfism, bone)
An internationally renowned center of excellence, the Valrose Institute of Biology (iBV) is a tripartite CNRS - Inserm - Université Côte d'Azur institute. Made up of 28 research teams, bringing together around 300 people from all over the world (20-30 different nationalities), the iBV is located in Nice on the Valrose Campus and the Valombrose Campus (Pasteur tower). The iBV teams study fundamental questions in life sciences and health such as the biology of organ development, the molecular pathology of cancer, diabetes, obesity, reproductive biology, etc. with multidisciplinary approaches in molecular biology, cell biology, genetics, imaging, genomics, and bioinformatics. Research at the iBV has access to a wide range of biological models (Drosophila, cell lines, yeast, nematodes, sea urchins, zebrafish, mice) and technology platforms providing the most advanced equipment for light microscopy, cytometry, histology, and biochemical purification.