Rentrée 2026 de l'Académie 4 "Complexité et diversité du vivant"

Vous êtes invités à la Rentrée de l'académie 4 qui se tiendra le 12 novembre prochain à l'IPMC à SOPHIA-ANTIPOLIS.

Cette matinée sera consacrée à la présentation de 10 projets de recherche sélectionnés en 2026 par l'Académie 4.
Ce sera l'occasion de découvrir la diversité de ces projets interdisciplinaires et de favoriser les échanges collaboratifs. 

Les présentations se tiendront en anglais.

L'accueil se fera à partir de 8h30.

Merci de confirmer votre présence à academies.excellence4@univ-cotedazur.fr. 


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You are invited to Academy 4 Kickoff Event, which will be held on November 12th at IPMC in SOPHIA-ANTIPOLIS.

This morning will be devoted to the presentation of 10 research projects selected in 2026 by Academy 4.
This will be an opportunity to explore the diversity of these interdisciplinary projects and to foster collaborative exchanges. 

The presentations will be held in English.

A coffee reception will begin at 8:30 am.

Please confirm your attendance by emailing academies.excellence4@univ-cotedazur.fr. 


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Modérateur: Guillaume Drin, président du conseil scientifique de l'Académie 4 
Chairperson: Guillaume Drin, président of the scientific council of the Academy 4


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Programme

8h30 Accueil / opening

9h00 Le mot de Pascal Barbry, coordinateur de l'Académie 4  / Opening remarks by Pascal BARBRY, Coordinator of Academy 4

9h10 TripMod - Resource allocation modelling in a multi-trophic plant-symbiont-pest system
By Pierre Frendo, ISA & Valentina Baldazzi, INRIA
Key words: Nitrogen fixing symbiosis, pea, Rhizobium leguminosarum, pea aphid, modelling.

9h30 DravNet - Network Mechanisms of Brain Dysfunction in Dravet Syndrome
By Fabrizio Capitano, IPMC & Etienne Tanre, INRIA 
Partners: Massimo Mantegazza, Patricia Reynaud Bouret
Key words: Epilepsy, Dravet Syndrome, Electrophysiology, Stochastic models, States transition, Functional connectivity

9h50 SEMANTICROSS - Neurocognitive mechanisms underlying semanticization across species
By Ingrid Bethus, IPMC & Raphaël Fargier, BCL
Key words: Neural basis of cognition, systems and computational neuroscience, learning, semantic, language
10h30 SPLENOCODE - Decoding the splenic neural code of inflammation: a transdisciplinary pilot towards nerve-based, real-time biomarkers of inflammatory disease activity
By Philippe Blancou, IPMC &  Olivier Meste, I3S
Key words:  bioelectronic medicine; neuro-immune interface; splenic nerve; neurogram; peripheral nerve decoding; real-time biomarker; machine learning; biomedical signal processing; rheumatoid arthritis; sympathetic drive; interspike intervals.

10h50 SERPIDUO - From Chemical Screening to Biological Validation: An Interdisciplinary Approach to Developing Novel SERPINE1 Inhibitors to Overcome Immunotherapy Resistance in Renal Cancer 
By Maeva Dufies, IRCAN & Cyril Ronco, ICN
Key words:  SERPINE1/PAI-1 ; carcinome rénal à cellules claires ; immunothérapie anti-PD-1; chimie médicinale ; inhibiteur pharmacologique

11h10 NUC-MECH-MEL - Nuclear deformation and mechanical modelling of melanoma phenotypic plasticity
By Mickael Ohanna, C3M &  Rachele Allena, LJAD
Partners : Emmanuèle Helfer-Cozic, CNRS Research Director, Aix-Marseille Université, CINaM
Key words:  Melanoma; phenotypic plasticity; LMNB2; nuclear envelope remodeling; nuclear deformability; confined migration; mechanobiology; mechanical modelling; therapy resistance; interdisciplinary training.

11h30 MorphoZIP - Testing an adhesion-mediated zipper during Drosophila mesoderm internalization
By  Matteo Rauzi, iBV & Grégoire Malandain, i3S
Key words : Drosophila gastrulation; mesoderm internalization; zippering; E-cadherin; apical-basal polarity; 4D segmentation; mechanobiology

11h50 PRIMA - Protein Redesign with Immunogenicity Mitigation Algorithms
By Patrick Brest, IRCAN & Edoardo Sarti, INRIA
Partners: Frédéric Cazals, Olivier Croce & Christina Cayron
Key words: Shared epitopes, Computational de-immunogenisation, reporter proteins, Protein language models, Differential tissue expression, Rational design, arDCA, Predictive immunogenicity

12h10 SAMBA - Symbiodiniaceae Attraction in Marine Behavioral Analysis
By Stéphanie Barnay-Verdier, Campus Valrose & Philippe Thomen, INPHYNI
Partners: Paola Furla ; Thamilla Zamoum ; Mohamed Mehiri

12h30 Discussions autour d'un buffet offert par l'Académie 4, en extérieur si le temps le permet / Discussions over a buffet provided by Académie 4; outdoors, weather permitting.