Axes de recherche

L'IDEX UCA^JEDI s’articule autour de plusieurs structures, dont 5 «académies d’excellence » qui ont pour mission de créer et favoriser l’émergence de nouvelles dynamiques scientifiques transdisciplinaires fortes, capables de devenir des pôles de référence en matière de Recherche, Formation et Innovation.

Les 5 académies recouvrent en elles-mêmes des thématiques transdisciplinaires :

Académie A1 : « Réseaux, information et société numérique »
Académie A2 : «Systèmes complexes »
Académie A3 : «Espace, environnement, risque et résilience »
Académie A4 : « Complexité et diversité du vivant»
Académie A5 : «Homme, idées et milieux »

Agenda

[REBICA 2024] REncontre annuelle BIoinformatique à Université Côte d'Azur 1er juillet 2024 INSPE NICE

Nice-Seq Seminar Series

The goal of this series is to have Crossdisciplinary Seminars from people working in NICE - VILLEFRANCHE - SOPHIA area who are interested in Next Generation Sequencing Approaches.

The first four editions were exclusively centered on Methods, Protocols, Analyses and Applications. The series are now opened to other Bio-Informatic Approaches. 
Presentations are given every 3 months by PhD students, Postdocs, Engineers and Researchers .

The venue rotates between different institutes and visioconference.

We hope that you will be interested in attending and contributing !
Press here to register to the mailing list.


ORGANISERS

Pascal BARBRY- IPMC - pascal.barbry@univ-cotedazur.fr
Christian BRAENDLE- iBV - christian.braendle@univ-cotedazur.fr
Richard COPLEY- UPMC - LBDV - richard.copley@obs-vlfr.fr
Etienne DANCHIN - ISA INRAE - etienne.danchin@inra.fr
Gianni LITI - IRCAN - gianni.liti@univ-cotedazur.fr
Michele TRABUCCHI - C3M - michele.trabucchi@univ-cotedazur.fr
Carole BARON - Université Côte d'Azur - carole.baron@univ-cotedazur.fr

ARCHIVES

• 
  17th NICE_SEQ SEMINAR SERIES, May 22nd, 3:30-5:45pm, IBV
• 
  15th NICE_SEQ SEMINAR SERIES, September 2nd 2022, 3-6:30pm, IRCAN
• 
  14th NICE_SEQ SEMINAR SERIES, September 17th 2021, 2-6pm
• 
  12th NICE_SEQ SEMINAR SERIES_March 19th 2021
• 
  11th NICE_SEQ SEMINAR SERIES_Nov 27th 2020
• 
  10th NICE_SEQ SEMINAR SERIES_April 2nd 2020
• 
  9th NICE_SEQ SEMINAR SERIES_Oct 3rd 2019
• 
  8th NICE_SEQ SEMINAR SERIES_June 28th 2019
• 
  7th NICE_SEQ SEMINAR SERIES_March 8th 2019
• 
  6th NICE_SEQ SEMINAR SERIES_Jan 11th 2019
• 
  5th NICE_SEQ SEMINAR SERIES_June 8th 2018
• 
  4th NICE_SEQ SEMINAR SERIES_March 16th 2018
• 
  3rd NICE_SEQ SEMINAR SERIES_Dec 15th 2017
• 
  2nd NICE_SEQ SEMINAR SERIES_Sept 8th 2017
• 
  1st NICE_SEQ SEMINAR SERIES_June 2nd 2017

JOBIM@UnivCotedAzur

Actualités


Archives

• 
  JOBIM 2021 à l'Université Côte d'Azur

 

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ABOUT US

Unraveling the mysteries of obesity, that’s the mission Adipo-Cible is pursuing.

Since November 2023, the consortium has officially brought together 21 fundamental and clinical research teams and one start-up toward a common goal: to understand why the adipose tissue dysfunctions in individuals with obesity and to develop personalized treatment for the disease.

The aim of ADIPOCIBLE is to be an international actor focusing on the adipose tissue dysfunction especially on the inflammation and fibrosis development

1- Obesity, a complex chronic disease

With more than one billion people suffering from obesity worldwide, it has become the most common chronic disease. The prevalence of obesity has continued its steep rise in the last decades, globally doubling among adults since 1990, and quadrupling among teenagers.

The World Health Organization defines obesity as a multifactorial, hence complex chronic disease as it involves an excessive deposition of adipose tissue that may harm the health. Indeed, people suffering from obesity are at risk of developing numerous pathologies such as cardiovascular diseases, type 2 diabetes, and certain types of cancer, which not only contribute to the world morbidity and mortality, but also impose a substantial economic burden.

Although therapeutic strategies have recently advanced, managing obesity remains complex and often ineffective due to the multifaceted nature of the disease. Notably, long-term results from dietary and physical activity modifications are modest. Therefore, it is urgent to identify the physiological factors underlying this disease at the genetic, cellular, and molecular levels to stem the rising number of cases.

2-  Stronger together

The Adipo-Cible research group aims to deepen the understanding of obesity through a multidisciplinary approach. Adipo-Cible unites researchers from diverse fields, including biology, chemistry, and mathematics, to establish a continuum of fundamental, translational, and clinical research around three main objectives:

- To unravel the mechanisms involved in adipose tissue dysfunction.
- To identify biomarkers of weight regain after metabolic and bariatric surgery and develop personalized treatments using predictive algorithms.
- To develop personalized nutritional and exercise programs, as well as surgical and endoscopic interventions, utilizing artificial intelligence to enhance and sustain weight loss efficacy.

 

ORGANIZATION

Two co-directors:
- Pr Antonio Iannelli
- Pr Christian Roux.

A Scientific Advisory Board:
- Pr A Iannelli,
- Pr CH Roux,
- Dr M Cormont,
- Dr EZ Amri,
- Dr P Tanti,
- Dr P Gual,
- Pr F Cherikh
- Dr V Lanoue.

The people:
- 7 clinicians and their team,
- 13 fundamental and transversal research teams,
- 1 start-up.

RESEARCH

1. Our Clinicians

- Rodolphe Anty
- Thierry Bège
- Faredj Cherikh
- Nicolas Chevalier
- Antonio Iannelli
- Christian Roux
- Stéphane Schneider
- Geoffroy Vanbiervliet

2. Our Biologists

- Cellular and Molecular Regulation of Fat Mass (CMRFM), iBV http://ibv.unice.fr/research-team/amri/

- Genomics & Evolution in Neuro-Endocrinology (GENE), IPMC https://www.ipmc.cnrs.fr/cgi-bin/site.cgi

- ImmunoSurveillance in Aging & Cancer (ISAC), IRCAN https://www.ircan.org/en/research/julien-cherfils-vicini

- Maintaining Autonomy, LAMHESS https://lamhess.univ-cotedazur.fr/projets-scientifiques/maintien-de-lautonomie

- Chronic Liver Diseases Associated with Obesity and Alcohol (LIVDISEASES), C3M https://www.c3m-nice.fr/en/Teams/team-08

- Myeloid Cell Immunometabolism (MCI), LP2M https://lp2m.univ-cotedazur.fr/axes-de-recherche/cellules-myeloides-et-metabolisme

- Insulin Resistance in Obesity and Type 2 Diabetes (IROD), C3M https://www.c3m-nice.fr/equipes/equipe-07/

- Vessel Formation in Development and Disease (VFDD), iBV http://ibv.unice.fr/research-team/wagner/

3. Our Chemists

- Chemical Senses and Simulations (ChemSenSim), ICN https://lab.chemsensim.fr/

4. Our Mathematicians

- Signaux, Images et Systèmes (SIS), i3S https://www.i3s.unice.fr/fr/axes-de-recherche/sis

- Analysis and Control of Unsteady Models in Engineering Sciences (ACUMES), INRIA https://team.inria.fr/acumes/

- 3IA https://3ia.univ-cotedazur.eu/research/chair-holder-olivier-humbert

5. Our Start-Up

- ExAdEx Innov https://exadex-innov.com/

 

EVENTS

Winter School Adipo-cible 2024

RECENT PUBLICATIONS

- Amri, E.-Z., 2024. Beige or brite adipocytes of the adipose organ: Link with white and brown adipocytes. Ann Endocrinol (Paris) 85, 253–254. https://doi.org/10.1016/j.ando.2024.05.002

- Benamran, D., Chierici, A., Temime, V., Drai, C., Iannelli, A., 2024. Results of sleeve gastrectomy conversion to Roux-en-Y gastric bypass on gastroesophageal reflux disease symptoms and proton pump inhibitors use evolution over time. J Gastrointest Surg S1091-255X(24)00494–3. https://doi.org/10.1016/j.gassur.2024.06.001

- Bertola, A., Gallerand, A., Ivanov, S., 2022. Immune cell involvement in brown adipose tissue functions. Discov Immunol 1, kyac007. https://doi.org/10.1093/discim/kyac007

- Caci H, Chierici A, Iannelli A. Attention-deficit/hyperactivity disorder in adolescent and adult candidates for metabolic and bariatric surgery: A systematic review and meta-analysis. Obesity Reviews. 2024;e13802. doi:10.1111/obr.13802

- Díaz Del Moral, S., Benaouicha, M., Villa Del Campo, C., Torres, M., Wagner, N., Wagner, K.-D., Muñoz-Chápuli, R., Carmona, R., 2023. Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage. J Cardiovasc Dev Dis 10, 211. https://doi.org/10.3390/jcdd10050211

- Sanchez, C., Colson, C., Gautier, N., Noser, P., Salvi, J., Villet, M., Fleuriot, L., Peltier, C., Schlich, P., Brau, F., Sharif, A., Altintas, A., Amri, E.-Z., Nahon, J.-L., Blondeau, N., Benani, A., Barrès, R., Rovère, C., 2024. Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity. Brain, Behavior, and Immunity 117, 330–346. https://doi.org/10.1016/j.bbi.2024.01.216

- Temime, V., Ghanem, O.M., Heimbach, J.K., Diwan, T.S., Tranchart, H., Abdallah, H., Blanchard, C., Lontrichard, M., Reche, F., Borel, A.-L., Belluzzi, A., Foletto, M., Manno, E., Poghosyan, T., Chierici, A., Iannelli, A., 2024. Outcomes of bariatric surgery in the setting of compensated advanced chronic liver disease associated with clinically significant portal hypertension: a multicenter, retrospective, cohort study on feasibility and safety. Int J Surg 110, 3562–3570. https://doi.org/10.1097/JS9.0000000000001310

FOCUS OF THE MONTH

Coming soon

CONTACT

Dr Vanessa Lanoue BSc, MSc, PhD
Project officer for the Adipo-Cible consortium
Tel +33 7 73 53 02 91
Email vanessa.lanoue@univ-cotedazur.fr
https://www.linkedin.com/company/adipo-cible